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My lab:
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operant
Operant control slows progression of ALS
Amyotrophic Lateral Sclerosis (ALS, also known as 'Lou Gerhig's disease') is a debilitating and eventually fatal disease in which patients suffer from progressive paralysis. However, they are only losing their movements,...[more]
operant   ALS   control   locked-in   
Posted on Thursday 09 November 2006 - 15:06:44

operant pain control
Operant conditioning is the means by which we learn to control our environment. It works by generating variable behavior ("trying out") and then looking, which of the variables in the environment ("stimuli") vary in the ...[more]
operant   control   pain   analgesic   
Posted on Friday 03 November 2006 - 09:27:22

World-learning and self-learning: two biological processes underlying operant conditioning
Our article entitled "The biology of psychology: Simple conditioning?" has just appeared in Communicative & Integrative Biology. It is an open access article, so it's free. My postdoc Julien Colomb and I wrote it aft...[more]
operant   drosophila   world-learning   self-learning   habit formation   
Posted on Wednesday 16 December 2009 - 17:44:25

Prep. #6: maybe increase the stimulation intensity?
In my attempts to establish operant learning in isolated leech ganglia I'm now at preparation number 6. In my last post, I promised to show some screenshots of the software I'm using, WinEDR. Here's a screenshot of the p...[more]
leech   operant   nervous system   neuroscience   learning   decision-making   
Posted on Wednesday 08 September 2010 - 02:22:10

Prep. #7: controls are important
This is preparation number seven in my attempts to establish operant learning in isolated leech ganglia and it's a control preparation, which means I'm just stimulating it every three minutes at ganglion 18 for an hour a...[more]
leech   operant   nervous system   neuroscience   learning   decision-making   
Posted on Thursday 09 September 2010 - 01:47:35

Prep. #8: the first yoked control
The yoked control in operant conditioning 'yokes' one animal to another in terms of stimuli received. In my attempts to establish operant learning in isolated leech ganglia, if one preparation received a given number of ...[more]
leech   operant   nervous system   neuroscience   learning   decision-making   
Posted on Friday 10 September 2010 - 01:25:29

Operant conditioning of a reflex?
Ever since I got into operant conditioning now over a good dozen years ago, I was aware that there was a researcher in New York studying operant learning in rats in a very unusual experimental setup. His lab triggers the...[more]
SfN2008   operant   H-reflex   wolpaw   
Posted on Sunday 16 November 2008 - 16:25:59

Prep. #9: another yoked control following the trend
Somehow, I didn't really manage to adjust the posterior stimulation properly in this 9th preparation in my attempts to establish operant learning in isolated leech ganglia, it generated a swim/crawl ratio of 9-1. Don't k...[more]
leech   operant   nervous system   neuroscience   learning   decision-making   
Posted on Tuesday 14 September 2010 - 02:12:52

Flies are creatures of habit, too
My latest paper has appeared a few days ago at Current Biology, with the title "Mushroom-bodies regulate habit formation in Drosophila". In it I describe experiments which I interpret as showing habit formation in fruit ...[more]
Drosophila   operant   habit   habit formation   
Posted on Wednesday 08 July 2009 - 20:59:05

Prep. #10: the most boring control of them all - usually
Obviously, when you just observe the experiment and don't do anything to it at all, that's the most boring experiment one can think of. Nothing happens, in my special case of attempting to establish operant learning in ...[more]
leech   operant   nervous system   neuroscience   learning   decision-making   
Posted on Wednesday 15 September 2010 - 02:36:31

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