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My lab:
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Up next at the Royce Conference of University of Alberta was a Skype presentation from Chicago by a former postdoc in Clayton Dickson's lab, Kyle Mathewson on electrode recordings in epileptic patients. He looked at slow brain wave oscillations in sleeping patients and how they relate to memory consolidation. The recordings come from a whole night's sleep with implanted electrodes recording single cell activity in various parts of their cortex. In deep-sleep phases, slow wave oscillations appear ot be more common than in awake or less deep sleep phases. The oscillations he detected matched the EEG oscillations measured on the patients' scalp. He specifically looked at data from those electrodes which were placed in the medial temporal lobes, the brain structures most commonly associated with memory processes. These data mimic those of rats, such that slower frequency oscillations correlate with deeper sleep phases (as measured by EEG). He found that there are gamma power oscillations nested in theta frequency waves. This phase-amplitude nesting is correlated with sleep stage. He showed two YouTube videos with some of the data, but the videos are set to private, so I can't link to them here.
Posted on Friday 02 March 2012 - 22:29:13 comment: 0
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